Advanced NMR Approaches for a Detailed Structure Analysis of Natural Products

• FUKUSHI Eri

  Graduate School of Agriculture, Hokkaido University

抄録

Some new nuclear magnetic resonance (NMR) approaches to elucidate chemical structures, which have not been determined by routine NMR methods, are presented. Selective detection of methine (CH), methylene (CH₂), or methyl (CH₃) signals in each subspectrum by editing NMR methods was utilized to reduce the complexity in crowded spectra. It also increased the peak separation and enhanced the sensitivity by limiting the measuring area of the 2D spectra. Several 2D methods to measure ^2,3J_CH values, which are useful for stereochemical assignment are then introduced. To determine the structure of a highly hydrogen-deficient molecule, efficient correlation methods for long-range ¹³C–¹³C coupling and ¹H-¹⁵N HMBC are also described.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 70 (8), 1803-1812, 2006

  公益社団法人 日本農芸化学会

キーワード

• editing NMR
• E-HSQC
• E-HSQC-ROESY
• DEPT C–C relay
• natural product

詳細情報

• CRID: 1390001206479555584
• NII論文ID: 10018527703
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.50663
• ISSN: 13476947
• ISSN: 09168451
• HANDLE: 2115/14726
• NDL書誌ID: 8040070
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8040070
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.50663
• 本文言語コード: en
• データソース種別:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可