Structure-Activity Relationships of Triterpenoid Saponins on Fruiting Body Induction in<i>Pleurotus ostreatus</i>

  • MAGAE Yumi
    Department of Applied Microbiology, Forestry and Forest Products Research Institute
  • OHARA Seiji
    Department of Biomass Chemistry, Forestry and Forest Products Research Institute

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  • Structure-Activity Relationships of Triterpenoid Saponins on Fruiting Body Induction in Pleurotus ostreatus

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To elucidate the structure-activity relationships of saponin on fruiting body induction in Pleurotus ostreatus, monodesmosidic saponins comprising a triterpenoid and glucose residues were synthesized. Betulin, a triterpenoid present in Birch bark, was used as the aglycon. The fruiting body induction activity increased with the number of glucose residues, from one to four. The most active betulinic saponin was betulin-3-yl β-D-(4-O-β-D-maltotriosyl)-glucoside.

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