A New Double-Stranded RNA Binding Protein (DRBP-120) Is Associated with Double-Stranded RNA-Activated Protein Kinase (PKR)
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- WATANABE Shuji
- Department of Physiology, School of Medicine, Iwate Medical University
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- YAMASHITA Tetsuro
- Department of Agro-Bioscience, Faculty of Agriculture, Iwate University
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- TAIRA Hideharu
- Department of Agro-Bioscience, Faculty of Agriculture, Iwate University
書誌事項
- タイトル別名
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- New Double Stranded RNA Binding Protein DRBP 120 Is Associated with Double Stranded RNA Activated Protein Kinase PKR
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Double-stranded RNA-activated protein kinase (PKR) plays an important role in interferon-induced antiviral responses, and is also involved in intracellular signaling pathways, including the apoptosis, proliferation, and transcription pathways. In this study, a new 120-kDa PKR-associated protein designated double-stranded RNA binding protein (DRBP)-120 was identified using co-immunoprecipitation with anti-PKR antiserum and two-dimensional electrophoresis. Furthermore, DRBP-120 is a double-stranded RNA (dsRNA)-binding protein, and it was detected in both the cytoplasm and the nucleus of HeLa cells associated with PKR.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 70 (7), 1717-1723, 2006
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206479875200
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- NII論文ID
- 10018529338
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 7998040
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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