Expression of ADP-Ribosylation Factor-Like Protein 8B mRNA in the Brain Is Down-Regulated in Mice Fed a High-Fat Diet

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著者

    • SUMIYOSHI Naoki
    • Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University
    • EGUCHI Yuko
    • Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University
    • KATO Norihisa
    • Department of Molecular and Applied Bioscience, Graduate School of Biosphere Science, Hiroshima University

抄録

A differential display was performed to analyze differential gene expression in the brains of mice in association with dietary high beef-tallow. Consumption of a high beef-tallow diet downregulated the expression of ADP-ribosylation factor-like protein 8B (Arl8B) mRNA in the brain. Arl8B mRNA was widely expressed in the mouse brain, including primary neuronal cells. The current study indicates that green fluorescent protein-fused Arl8B protein accumulated at the growth cones in primary neuronal cells, and that protrusions of human embryonic kidney 293 (HEK293) cells were significantly elongated by overexpression of Arl8B, suggesting an important role of Arl8B in neurite formation.

収録刊行物

  • Bioscience, biotechnology, and biochemistry  

    Bioscience, biotechnology, and biochemistry 70(7), 1798-1802, 2006-07-23 

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

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各種コード

  • NII論文ID(NAID)
    10018529672
  • NII書誌ID(NCID)
    AA10824164
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    09168451
  • NDL 記事登録ID
    7998270
  • NDL 雑誌分類
    ZR7(科学技術--農林水産--農産) // ZR2(科学技術--生物学--生化学) // ZP1(科学技術--化学・化学工業)
  • NDL 請求記号
    Z53-G223
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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