Repression of Secondary Metabolite Production by Exogenous cAMP in<i>Monascus</i>

• MIYAKE Tsuyoshi

  Industrial Technology Center of Okayama Prefecture

• ZHANG Ming-Yong

  Industrial Technology Center of Okayama Prefecture Japan Society for the Promotion of Science

• KONO Isato

  Industrial Technology Center of Okayama Prefecture

• NOZAKI Nobuyuki

  Industrial Technology Center of Okayama Prefecture

• SAMMOTO Hiroyuki

  Industrial Technology Center of Okayama Prefecture

書誌事項

タイトル別名

• Repression of Secondary Metabolite Production by Exogenous cAMP in Monascus

抄録

The cAMP signal pathway controls various biological functions, including secondary metabolism of filamentous fungi. We found that exogenous cAMP represses the production of lovastatin, red pigments, and citrinin in Monascus. Interestingly, a mutant MK-1 with increased lovastatin and red pigments production (Miyake, T., et al., Biosci. Biotechnol. Biochem., 70, 1154–1159 (2006)) was not influenced by cAMP on these productions, indicating that cAMP signaling might be lacking in MK-1.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 70 (6), 1521-1523, 2006

  公益社団法人 日本農芸化学会

キーワード

• <I>Monascus</I>
• secondary metabolite production
• cAMP
• repression
• mutant MK-1

詳細情報

• CRID: 1390001206479590016
• NII論文ID: 10018530555
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.50686
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 7959287
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7959287
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.50686
• 本文言語コード: en
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