Enzymatic Synthesis of Oligosaccharides and Neoglycoconjugates

• MURATA Takeomi

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

• USUI Taichi

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

抄録

Oligosaccharides involved in glycoconjugates play important roles in a number of biological events. To elucidate the biological functions of oligosaccharides, sufficient quantities of structurally defined oligosaccharides, are of limited availability by traditional purification methods, are required. Hence, chemical and enzymatic syntheses of oligosaccharides are becoming increasingly important in glycobiology and glycotechnology. In addition, oligosaccharides often occur as glycoconjugates attached to proteins or lipids. Hence, the development of simple and effective methods for synthesizing neoglycoconjugates such as neoglycoprotein and neoglycolipids is essential for an understanding of the biological function of these molecules. Here we review the most recent developments in the enzymatic synthesis of oligosaccharides and neoglycoconjugates.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 70 (5), 1049-1059, 2006

  公益社団法人 日本農芸化学会

キーワード

• enzymatic synthesis
• glycosidase
• glycosyltransferase
• neoglycoconjugate
• oligosaccharide

詳細情報

• CRID: 1390001206472813952
• NII論文ID: 10018530664
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.70.1049
• COI: 1:STN:280:DC%2BD283os1ygsQ%3D%3D
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 7925764
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7925764
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.70.1049
• 本文言語コード: en
• データソース種別:
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• 抄録ライセンスフラグ: 使用不可