Comparisons of Potentials for L-Lysine Production among Different Corynebacterium glutamicum Strains

• OHNISHI Junko

  BioFrontier Laboratories, Kyowa Hakko Kogyo Co., Ltd.

• IKEDA Masato

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

Bibliographic Information

Other Title

• Comparisons of Potentials for<scp>L</scp>-Lysine Production among Different<i>Corynebacterium glutamicum</i>Strains

Abstract

Corynebacterium glutamicum is an industrially important organism that is most widely used for the production of various amino acids. A defined L-lysine-producing mutant was generated by introduction of the lysC mutation (T311I) into each of six representative C. glutamicum strains. The resulting six isogenic mutants were compared for L-lysine production under traditional 30 °C conditions and industrially more advantageous 40 °C conditions. It was found that there were significant differences in yield and productivity, especially at 40 °C. These results indicate the diversity among C. glutamicum strains in fermentative characters, as well as the importance of selecting a strain with industrially best performance.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 70 (4), 1017-1020, 2006

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• <I>Corynebacterium glutamicum</I>
• <small>L</small>-lysine production
• isogenic mutants

Details

• CRID: 1390282681452889600
• NII Article ID: 10018532851
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.70.1017
• ISSN: 13476947
• ISSN: 09168451
• NDL BIB ID: 7900273
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7900273
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.70.1017
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed