Ursolic Acid Enhances Cyclooxygenases and Tumor Necrosis Factor-α Expression in Mouse Skin
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- IKEDA Yasutaka
- Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
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- MURAKAMI Akira
- Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
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- NISHIZAWA Takashi
- Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
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- OHIGASHI Hajime
- Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
書誌事項
- タイトル別名
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- Ursolic Acid Enhances Cyclooxygenases and Tumor Necrosis Factor-.ALPHA. Expression in Mouse Skin
- Ursolic Acid Enhances Cyclooxygenases and Tumor Necrosis Factor アルファ Expression in Mouse Skin
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抄録
An anti-inflammatory triterpenoid, ursolic acid (UA), has recently been found unexpectedly to induce the release of a pro-inflammatory mediator in resting macrophages. In this study, we found that topical applications of UA to mouse skin twice a week for 2 weeks significantly enhanced mRNA expression of cyclooxygenase (COX)-1, COX-2, and tumor necrosis factor-α, whereas its effect on tumor promotion was unclear.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 70 (4), 1033-1037, 2006
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206476222848
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- NII論文ID
- 10018532926
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 7900003
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可