Synthesis and Anti-Juvenile Hormone Activity of Ethyl 4-(2-Aryloxyhexyloxy)benzoates
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A series of ethyl 4-(2-aryloxyhexyloxy)benzoates was prepared and tested for their activity to induce precocious metamorphosis in larvae of the silkworm. Phenyl analog <B>5</B> showed activity comparable to that of the 6-methyl-3-pyridyl analog reported as a novel anti-JH agent. The activity of <B>5</B> could be fully counteracted by methoprene, a JH agonist. The ethoxycarbonyl group of <B>5</B> was essential for its activity.
- Agricultural and Biological Chemistry
Agricultural and Biological Chemistry 70(3), 746-748, 2006-03-23
Japan Society for Bioscience, Biotechnology, and Agrochemistry