Anti-Diabetic Effect of Alkaline-Reduced Water on OLETF Rats

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著者

    • Jin Dan JIN Dan
    • Department of Microbiology, Wonju College of Medicine, Yonsei University
    • YANG Eun Ju
    • Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University
    • LIM Soo Jung
    • Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University
    • RYANG Yong Suk
    • Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University
    • CHUNG Choon Hee
    • Department of Internal Medicine, Wonju College of Medicine, Yonsei University
    • PARK Seung Kyu
    • Department of Parasitology and Institutes for Basic Medical Science, Wonju College of Medicine, Yonsei University
    • LEE Kyu Jae
    • Department of Parasitology and Institutes for Basic Medical Science, Wonju College of Medicine, Yonsei University

抄録

Alkalin-reduced water (ARW) is known to exert several anti-cancer effects, as well as to scavenge reactive oxygen species (ROS) and reduce blood-glucose levels. This study was performed in order to determine the effects of ARW on the control of spontaneous diabetes in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.<BR>We assigned 16 male OLETF rats (4 wk) to two groups: an experimental group, which was given ARW, and a control group, which received laboratory tap water. From week 6 to 32, the body weight, lipid composition, and glucose levels in the blood of the rats were measured. The glucose levels of both groups tended to increase. However, the ARW group's glucose levels were significantly lower than those of the control group after 12 weeks (<I>p</I><0.05). The total cholesterol and triglyceride levels in the ARW group were found to be significantly lower than those of the control group during the experimental period.<BR>These results suggest that ARW spurred the growth of OLETF rats during the growth stage, and that long-term ingestion of ARW resulted in a reduction in the levels of glucose, triglycerides, and total cholesterol in the blood.

収録刊行物

  • Bioscience, biotechnology, and biochemistry  

    Bioscience, biotechnology, and biochemistry 70(1), 31-37, 2006-01-23 

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

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各種コード

  • NII論文ID(NAID)
    10018534960
  • NII書誌ID(NCID)
    AA10824164
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09168451
  • NDL 記事登録ID
    7791143
  • NDL 雑誌分類
    ZR7(科学技術--農林水産--農産) // ZR2(科学技術--生物学--生化学) // ZP1(科学技術--化学・化学工業)
  • NDL 請求記号
    Z53-G223
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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