Effects of Combined Administration of Quercetin, Rutin, and Extract of White Radish Sprout Rich in Kaempferol Glycosides on the Metabolism in Rats

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  • HASHIMOTO Takashi
    Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University
  • UEDA Yuko
    Division of Life Science, Graduate School of Science and Technology, Kobe University
  • OI Naomi
    Division of Life Science, Graduate School of Science and Technology, Kobe University
  • SAKAKIBARA Hiroyuki
    Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University
  • PIAO Chengyuan
    Division of Life Science, Graduate School of Science and Technology, Kobe University
  • ASHIDA Hitoshi
    Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University Division of Life Science, Graduate School of Science and Technology, Kobe University
  • GOTO Miho
    Division of Life Science, Graduate School of Science and Technology, Kobe University
  • KANAZAWA Kazuki
    Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University Division of Life Science, Graduate School of Science and Technology, Kobe University

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Abstract

Quercetin, rutin, the extract of white radish sprout rich in kaempferol glycosides, and their combination were intragastrically administered to Wistar rats to investigate the interactive metabolism of these flavonoids. The combined administration of these flavonoids changed the concentrations of the metabolites in plasma as compared with the concentrations after the administration of a single compound.

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