上顎骨に発生した筋線維腫の1例 [in Japanese] A case of myofibroma of the maxilla [in Japanese]
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Myofibroma is a rare benign localized or generalized proliferation of fibroblastic tissue occurring exclusively in infants or children. In the oral region, most lesions occur in the mandible, lip, buccal mucosa, and tongue, but and lesions arising in the maxilla are very rare. Myofibroma has an aggressive clinical presentation and is often over- treated because of an inappropriate diagnosis.<BR>We report a case of myofibroma arising in the left side of the maxilla of a 9-year-old girl and describe the differential diagnosis from other spindle cell lesions. Surgical resection of the tumor was performed under general anesthesia. Immunohistochemical staining was very useful for establishing the diagnosis, since histopathological diagnosis with conventional staining could not distinguish myofibroma from spindle cell tumors, especially fibrosarcoma. Fibrosarcoma is positive for vimentin and negative for anti-muscle-specific actin antibody (HHF-35), but this tumor was positive for both vimentin and HHF-35. These features led to the diagnosis of myofibroma.<BR>The patient has shown no signs of recurrence during 2 years of follow-up.
- Journal of Oral Surgery Society of Japan
Journal of Oral Surgery Society of Japan 50(12), 777-780, 2004-12-20
Japanese Society of Oral and Maxillofacial Surgeons