下顎骨に生じた線維肉腫の1例 [in Japanese] A case of fibrosarcoma of the mandible [in Japanese]
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Fibrosarcoma, a malignant tumor of fibroblasts, occurs rarely in the head and neck. This report describes a case of fibrosarcoma in the left side of the mandible in a 54-year-old man. He was referred to our department because of occlusal pain in the molar region of the left side of the mandible. Panoramic tomography showed a poorly defined radiolucent area extending from the second premolar of the left side of the mandible to the mandibular angle. Under the clinical diagnosis of a malignant tumor of the left side of the mandible, an incisional biopsy was performed. A mesenchymal malignant tumor was suspected. Surgical treatment comprising radical neck dissection, segmental resection of the left side of the mandible, and reconstruction of the mandible was performed under general anesthesia. Histopathological examinations of multiple sections and specially stained sections, as well as immunohistochemical studies, were performed. The final tissue analysis revealed a fibrosarcoma. After surgery, one course of combination chemotherapy with cyclophosphamide, vincristine, epirubicin and dacarbazine, (CYVADIC therapy) was administered. A 30-month follow-up showed no evidence of local recurrence or distant metastasis.
- Journal of Oral Surgery Society of Japan
Journal of Oral Surgery Society of Japan 50(11), 664-667, 2004-11-20
Japanese Society of Oral and Maxillofacial Surgeons