放射線治療によって消失した肉腫様の組織像を呈する肝細胞癌の歯肉転移の1例 Gingival metastasis from primary hepatocellular carcinoma with sarcomatoid changes responding to radiotherapy
Hepatocellular carcinoma (HCC) with sarcomatoid changes is a rare neoplasm more frequently associated with extrahepatic metastasis than ordinary HCC. A case of gingival metastasis from primary HCC with sarcomatoid changes is described. A 67-year-old man presented with a gingival tumor. The patient had a history of HCC, treated by percutaneous ethanol injection (PEIT) and transcatheter arterial embolization (TAE). Three years after treatment, recurrence and the gingival tumor were recognized. The gingival tumor was dark red and bled easily. Biopsy was carried out, and the diagnosis was a metastatic tumor from the HCC with sarcomatoid changes. The tumor size was so large that the patient complained of difficulty in mastication. Radiotherapy was used to shrink the gingival tumor. It was very effective, and the tumor disappeared in response to only 40 Gy irradiation. Complications of irradiation were not serious, and radiostomatitis resolved promptly. The gingival tumor has not recurred. The patient was able to eat more than before treatment. Radiotherapy of the gingival tumor improved the patient's quality of life.
日本口腔外科学会雑誌 50(8), 499-502, 2004-08-20
Japanese Society of Oral and Maxillofacial Surgeons