γ-グロブリン大量療法が有効であった特発性血小板減少性紫斑病を有する骨格性下顎前突症患者の周術期管理 Perioperative management using high-dose γ-globulin therapy for mandibular prognathism associated with idiopathic thrombocytopenic purpura
A case of mandibular prognathism in a 15-year-old woman with idiopathic thrombocytopenic purpura (ITP) is reported.<BR>In this patient, ITP had been diagnosed during preoperative orthodontic treatment. Since the preoperative laboratory data revealed a low platelet count of 5.5×10<SUP>4</SUP>/μl, the patient was given preoperative high-dose γ-globulin therapy (400mg/kg/day) for 5 days. On the day of the operation, the platelet count had increased to 12.0×10<SUP>4</SUP>/μl.Intraoral vertical ramus osteotomy was performed, and the amount of perioperative blood loss was 194g.After surgery, there was no abnormal bleeding, and the postoperative course was uneventful.<BR>High-dose γ-globulin therapy is considered a very useful and safe method for preoperative treatment of patients with ITP.
日本口腔外科学会雑誌 50(6), 404-407, 2004-06-20
Japanese Society of Oral and Maxillofacial Surgeons