摂食障害患者に発生した壊死性唾液腺化生の2例 [in Japanese] Two cases of necrotizing sialometaplasia in patients with eating disorders [in Japanese]
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Necrotizing sialometaplasia (NS) is a benign disease of the mucous-secreting glands that most commonly occurs in the palatal mucosa. It was first described by Abrams et al. in 1973 as an inflammatory disease characterized by coagulative necrosis of the minor salivary glands, marked squamous metaplasia of glandular acini and ducts, and even pseudoepitheliomatous hyperplasia. Etiologically, NS is thought to be caused by ischemia due to local tissue injury. We describe two cases of necrotizing sialometaplasia in a patient with bulimia and self-induced vomiting. The etiologic factors of NS are discussed. Initially, NS may be triggered by physical trauma with ischemia. Gastric juice irritation and side effects of drugs are considered to contribute to the development of NS.
- Journal of Oral Surgery Society of Japan
Journal of Oral Surgery Society of Japan 50(5), 293-296, 2004-05-20
Japanese Society of Oral and Maxillofacial Surgeons