乳房温存療法に伴う放射線照射後に発症したBOOP様肺炎の1例

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  • A CASE OF BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA (BOOP) INDUCED RADIOTHERAPY AFTER BREAST PRESERVING THERAPY

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We report the case of a 59-year-old woman who underwent conserving surgery for the left breast, and received chemotherapy and radiation therapy to the remainning part of the left breast. About five months after the termination of irradiation, cough and fever developed. Chest radiography and computed tomography showed an infiltrative shadow in the left lung. Various antibiotic therapies were performed but the laboratory data and radiographs showed detenoration. We clinically diagnosed this case as having Bronchiolitis Obliterans Organizing Pneumonia (BOOP) syndrome after radiation therapy. Corticosteroid treatment resulted in rapid clinical improvement. Thereafter, oral predonisolone was administered and gradually decreased. Nevertheless, new infiltrative shadows developed in the right lung. An increased dose of predonisolone resulted in rapid improvement of the clinical symptoms and chest radiograph abnormalities. Although the etiology of BOOP syndrome is unknown, it is important to remember that the BOOP syndrome may occur as a complication of breast-conserving therapy.

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