Research on Antihyperglycemic Drug Therapies in Patients with Type 2 Diabetes Mellitus in Japan (II): the Effectiveness on Glycemic Control (JDDM7)

• Kanatsuka Azuma

  Diabetes Center, Chiba Central Medical Center

• Kawai Koichi

  Kawai Clinic

• Hirao Koichi

  H.E.C. Science Clinic

• Oishi Mariko

  Oishi Internal Medicine Clinic

• Takagi Hirofumi

  School of Nursing, Faculty of Medicine, Toho University

• Kobayashi Masashi

  The First Department of Internal Medicine, Faculty of Medicine, University of Toyama

• Japan Diabetes Clinical Data Management Study Group

Bibliographic Information

Other Title

• ２型糖尿病患者における薬物療法に関する実態調査（ＩＩ）―薬物療法と血糖コントロール―（ＪＤＤＭ７）
• 2型糖尿病患者における薬物療法に関する実態調査(2)薬物療法と血糖コントロール(JDDM7)
• 2ガタ トウニョウビョウ カンジャ ニ オケル ヤクブツ リョウホウ ニ カンスル ジッタイ チョウサ 2 ヤクブツ リョウホウ ト ケットウ コントロール JDDM7
• —薬物療法と血糖コントロール—(JDDM7)

Abstract

To clarify the actual usage of oral hypoglycemic agents (OHA) and insulin preparations (INS) and their effectiveness on glycemic control in patients with type 2 diabetes mellitus in Japan, we analyzed clinical data collected from 34 institutes using CoDiC^®, an electronic system for diabetes data collection and management. In 15,553 type 2 diabetic patients registered with CoDiC^® from January to July 2003, 36% were treated with OHA monotherapy, 33% with OHA combination therapy, 11% with INS plus OHA combination therapy, and 20% with INS monotherapy. A cross-sectional survey of 14,099 patients whose HbA_1C data had been input CoDiC^® showed that glycemic control was excellent or good in 29%, fair in 49%, and poor in 22%. Among those undergoing OHA monotherapy control was the poorest in patients treated with sulfonylureas. It was poorer in patients treated with OHA combination therapy than in patients undergoing OHA monotherapy. Patients undergoing INS plus OHA combination therapy had the poorest glycemic control. Glycemic control was poor in 32% of those undergoing INS monotherapy. In a clinical setting, obtaining ideal glycemic control in many type 2 diabetic patients is therefore difficult with currently available pharmaceutical agents.

Journal

• Journal of the Japan Diabetes Society

  Journal of the Japan Diabetes Society 49 (12), 919-927, 2006

  THE JAPAN DIABETES SOCIETY

Keywords

• 2型糖尿病
• 血糖コントロール
• 経口血糖降下剤
• インスリン製剤
• 観察研究

Details

• CRID: 1390282679883271680
• NII Article ID: 130004510960
• NII Article ID: 10018656391
• NII Book ID: AN00166576
• DOI: 10.11213/tonyobyo.49.919
• ISSN: 1881588X
• ISSN: 0021437X
• NDL BIB ID: 8648776
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8648776
• Web Site: https://search.jamas.or.jp/link/ui/2007134695
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • CiNii Articles
  • Crossref
• Abstract License Flag: Disallowed