Stem cell therapies for injured spinal cord

• Okano Hideyuki

  Department of Physiology, Keio University School of Medicine

• Nakamura Masaya

  Department of Orthopedic Surgery, Keio University School of Medicine

• Toyama Yoshiaki

  Department of Orthopedic Surgery, Keio University School of Medicine

Abstract

Although it was long thought that the damaged adult central nervous system (CNS) cannot regenerate, spinal cord injury (SCI) is now an important target in regenerative medicine. A series of studies on stem cell-based therapies for SCI has led us to believe that neural stem/progenitor cells (NSPCs) are a promising source for neural tissue replacement therapy after SCI, when applied appropriately. In this review, we summarize our previous findings on stem cell therapies for SCI and discuss the future directions of this work.

Journal

• Ensho Saisei

  Ensho Saisei 26 (1), 18-28, 2006

  The Japanese Society of Inflammation and Regeneration

Keywords

• neural stem cells
• spinal cord injury
• IL-6
• chondroitin sulfate proteoglycan
• common marmoset
• human ES cells

Details

• CRID: 1390282680156304256
• NII Article ID: 10018657069
• NII Book ID: AA11508953
• DOI: 10.2492/jsir.26.18
• COI: 1:CAS:528:DC%2BD28Xis1WnsL4%3D
• ISSN: 18805795
• ISSN: 13468022
• Web Site: https://search.jamas.or.jp/link/ui/2006128735
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed