Enantioselective Epoxidation of Conjugated Z-Olefins with Newly Modified Mn(salen) Complex
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Chiral Mn(salen) complex <B>3</B> bearing a 1-ethyl-1-methylpropyl group at C3, C3′, C5, and C5′ was found to induce higher asymmetry in the epoxidation of conjugated <I>Z</I>-olefins, especially less nucleophilic ones, in the presence of 4-phenylpyridine <I>N</I>-oxide than complex <B>1</B> bearing a <I>t</I>-butyl group at the same carbons. The higher enantioselectivity was considered to be attributable to Me-in-plane conformation of the 1-ethyl-1-methylpropyl group at C3 and C3′.
- Chemistry Letters
Chemistry Letters 36(1), 46-47, 2007-01-05
The Chemical Society of Japan