Catalytic Asymmetric Synthesis and Optical Resolution of Planar Chiral Rotaxane
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Planar chiral rotaxanes were synthesized from crown ether and secondary ammonium salt via trialkylphosphane-catalyzed acylative end-capping. Their optical resolution was achieved by chiral HPLC after acylative neutralization of the ammonium group. When optically active trialkylphosphane <B>2</B> was used as the chiral acylation catalyst, optically active rotaxane (4.4% ee) was obtained.
- Chemistry Letters
Chemistry Letters 36(1), 162-163, 2007-01-05
The Chemical Society of Japan