A case of Churg-Strauss syndrome discovered with hematemesis

  • OKUDAIRA Keisuke
    Second Department of Internal Medicine, National Defense Medical College
  • KAWAGUCHI Atsushi
    Second Department of Internal Medicine, National Defense Medical College Department of Endoscopic and Photodynamic Medicine, National Defense Medical College
  • HOKARI Ryota
    Second Department of Internal Medicine, National Defense Medical College
  • NARIMATSU Kazuyuki
    Second Department of Internal Medicine, National Defense Medical College
  • HIGASHIYAMA Masaaki
    Second Department of Internal Medicine, National Defense Medical College
  • MATAKI Norikazu
    Second Department of Internal Medicine, National Defense Medical College
  • KATO Shingo
    Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical School
  • KOMOTO Syunsuke
    Second Department of Internal Medicine, National Defense Medical College
  • TSUZUKI Yoshikazu
    Second Department of Internal Medicine, National Defense Medical College Tsuzuki Clinic
  • NAGAO Shigeaki
    Second Department of Internal Medicine, National Defense Medical College Department of Endoscopic and Photodynamic Medicine, National Defense Medical College
  • ITOH Kazuro
    Second Department of Internal Medicine, National Defense Medical College
  • MIURA Soichiro
    Second Department of Internal Medicine, National Defense Medical College Department of Endoscopic and Photodynamic Medicine, National Defense Medical College

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Other Title
  • 吐血を契機に診断されたChurg-Strauss症候群の1例

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Abstract

A 68-years-old Japanese woman was hospitalized emergently because of hemorrhagic gastric ulcer. For the hospitalization periodC elevated levels of white blood cell countC eosinophilic leucocyte countC serum IgE and positive MPO-ANCA were recognized. With considering clinical course and these laboratory findingsC we diagnosed Churg-Strauss syndrome (CSS). Steroid therapy in combination with cyclophosphamide was effective. CSS is a rare diseaseC but we should discriminate this disease when we encounter gastrointestinal bleeding of unknown etiologyC especially PPI-resistant gastric ulcer.<br>

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