A case of miliary tuberculosis complicating acute Q fever

  • SUMIDA Yoshio
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • KANEMASA Kazuyuki
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • FUKUMOTO Kohei
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • KATOH Naho
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • IMAMURA Shigeyoshi
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • ITOH Yoshito
    Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine
  • OKANOUE Takeshi
    Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine

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Other Title
  • 急性Q熱を合併した粟粒結核の1例

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Abstract

A 73-year-old man was admitted with fever and abnormal liver function test. After admission, his fever persisted in spite of administrating a variety of antibiotics. He was diagnosed as acute Q fever on the basis of a high titer of IgM antibodies against phase II Coxiella burneti. His fever resolved after starting minocycline, but biliary enzymes continued to be elevated. Transbronchial lung biopsy and percutaneous liver biopsy revealed caseating granulomas and Mycobacterium tuberculosis was detected by culture. Miliary tuberculosis was diagnosed and his biliary enzymes declined after starting therapy with antituberculous drugs. This report of miliary tuberculosis complicating acute Q fever is a valuable and unprecedented case.<br>

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