Mass Spectrometric Elucidation of Phenolic Oxidation Processes with Cu2+-Adduct

• HAYASHI Akio

  School of Material Sciences, Japan Advanced Institute of Science and Technology

• TANIGUCHI Noriko

  School of Material Sciences, Japan Advanced Institute of Science and Technology

• TSUJIMOTO Kazuo

  School of Material Sciences, Japan Advanced Institute of Science and Technology

• KUBO Isao

  Department of Environmental Science, Policy and Management, University of California

Bibliographic Information

Other Title

• Mass Spectrometric Elucidation of Phenolic Oxidation Processes with Cu〔2+〕-Adduct

Abstract

Formation of ε complex with 2-hydroxy-6-[8′(Z),11′(Z),14′-pentadecatrienyl]benzoic acid (anacardic acid) and copper ion in the respective ratios of 2 : 1 and 1 : 1 at room temperature was observed by electrospray ionization mass spectrometry. The oxidation of 3-(3,4-dihydroxyphenyl)alanine (DOPA) in the presence of anacardic acid showed competitive inhibition with temporary reduction from dopaquinone to DOPA. In the oxidation of neurotensin, the oxidized products, dopaquinone-derivatives, were observed. Mass spectrometry revealed that the enzymatic oxidation of tyrosine residue is inhibited by anacardic acid.

Journal

• Journal of the Mass Spectrometry Society of Japan

  Journal of the Mass Spectrometry Society of Japan 55 (1), 7-13, 2007

  The Mass Spectrometry Society of Japan

Keywords

• ESI
• Anacardic acid
• DOPA
• Neurotensin
• Antioxidation

Details

• CRID: 1390001206494639616
• NII Article ID: 10018702948
• NII Book ID: AN0010555X
• DOI: 10.5702/massspec.55.7
• ISSN: 18804225
• ISSN: 18843271
• ISSN: 13408097
• NDL BIB ID: 8675173
• Web Site: http://hdl.handle.net/10119/4629
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8675173
• Web Site: http://www.jstage.jst.go.jp/article/massspec/55/1/55_1_7/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed