バイオデバイスの飛行時間型二次イオン質量分析イメージング

書誌事項

タイトル別名
  • Time-of-Flight Secondary Ion Mass Spectrometry Imaging of Biodevices
  • バイオデバイス ノ ヒコウ ジカンガタ 2ジ イオン シツリョウ ブンセキ イメージング

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抄録

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging provides ten-nanometer-scale chemical images of biodevices. It is one of the most sensitive surface analysis methods and has recently been applied in life sciences. TOF-SIMS is useful for the evaluation of biodevice surfaces, because it provides ten-nanometer-scale mapping and chemical structures of immobilized proteins on devices. In addition, TOF-SIMS requires no pretreatment of samples, such as labeling with a fluorescent probe or coating with metallic thin films. In this paper, the principles of TOF-SIMS and data analysis methods are introduced, and some examples of biodevice observation with TOF-SIMS are described.

収録刊行物

  • 質量分析

    質量分析 55 (1), 33-38, 2007

    一般社団法人 日本質量分析学会

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