Malignant Lymphoma of the Rectum in a Patient with Systemic Lupus Erythematosus

DOI Web Site 1 Citations 23 References
  • Shimazaki J.
    Fourth Department of Surgery, Tokyo Medical University, Kasumigaura Hospital
  • Watanabe Y.
    Fourth Department of Surgery, Tokyo Medical University, Kasumigaura Hospital
  • Nakachi T.
    Fourth Department of Surgery, Tokyo Medical University, Kasumigaura Hospital
  • Ubukata H.
    Fourth Department of Surgery, Tokyo Medical University, Kasumigaura Hospital
  • Nakada I.
    Fourth Department of Surgery, Tokyo Medical University, Kasumigaura Hospital
  • Tabuchi T.
    Fourth Department of Surgery, Tokyo Medical University, Kasumigaura Hospital

Bibliographic Information

Other Title
  • 全身性エリテマトーデスに合併した直腸原発悪性リンパ腫の１例

Search this article

Abstract

A 71-year-old woman with systemic lupus erythematosus complained of anal bleeding. Barium enema and colonoscopy revealed an elevated tumor above the peritoneal reflection of the rectum. A biopsy specimen showed no specific findings other than chronic inflammation. To establish a pathological diagnosis, a low-anterior resection with lymph node dissection was performed. The resected tumor measured 4.0 cm in maximal diameter. Microscopically, it was composed of diffuse proliferation of atypical lymphoid cells, which were positive for CD20, but negative for CD5, on immunohistochemical staining. The tumor was diagnosed as a B-type non-Hodgkin's lymphoma, with low-grade features : mucosal associated lymphoid tissue (MALT) type. The dissected lymph node showed no definite evidence of lymphoma cell infiltration, and this lesion was diagnosed as a clinical stage I rectal lymphoma.<br>Some patients with autoimmune disorders associated with hemopoietic organ-related cancer, especially malignant lymphoma, have been previously reported in the literature. However, patients with autoimmune disorders associated with primary colorectal lymphoma are rare. We report a case of primary rectal lymphoma in a patient with systemic lupus erythematosus, and discuss this rare case.

Journal

Citations (1)*help

See more

References(23)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top