INCIDENCE OF NONHEMOLYTIC TRANSFUSION REACTION DUE TO IMMUNOLOGICAL REACTIONS

• Kurata Yoshiyuki

  Department of Blood Transfusion, Osaka University Hospital

• Shimizu Masaru

  Department of Clinical Pathology, Kyorin University School of Medicine

• Okazaki Hitoshi

  Japanese Red Cross Society, Blood Service Headquarters, Central Blood Institute

• Takamoto Shigeru

  Department of Blood Transfusion, Aichi University of Medical School

Bibliographic Information

Other Title

• 免疫学的機序による非溶血性輸血副作用頻度実態調査報告

Abstract

Nonhemolytic transfusion reactions (NHTR), such as urticaria or fever, are frequently experienced after transfusion. These reactions are seldom reported to the transfusion division or regional blood center because these are not particularly severe. Therefore, accurate data on the incidence of NHTR are scarce. We surveyed 216 hospitals with a comprehensive reporting system for these reactions about the incidence of NHTR. The study periods were the first 6 months of 2004 and of 2005.<br>We received replies from 160 hospitals (reply rate, 74%). Total RBCs, platelets and fresh frozen plasma transfused during the study periods were 365,513 bags, 129,741 bags and 182,460 bags, respectively. The most frequently experienced NHTR was urticaria by platelets, with an incidence per bag of 2.76% in 2004 and 2.79% in 2005. The second was itching by platelets, with an incidence of 0.62% and 0.54%, respectively, followed by fever by RBCs, at 0.41% and 0.40%, respectively, and fever by platelets, at 0.35% and 0.34%, respectively.<br>The incidence of NHTR per bag of platelets did not change before and after prestorage leukocyte reduction.

Journal

• Japanese Journal of Transfusion and Cell Therapy

  Japanese Journal of Transfusion and Cell Therapy 53 (1), 43-46, 2007

  The Japan Society of Transfusion Medicine and Cell Therapy

Keywords

• adverse effect
• nonhemolytic transfusion reaction
• immunological reaction
• incidence

Details

• CRID: 1390282680250226176
• NII Article ID: 10018733140
• NII Book ID: AA12159645
• DOI: 10.3925/jjtc.53.43
• ISSN: 18830625
• ISSN: 18813011
• Web Site: https://search.jamas.or.jp/link/ui/2007164142
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed