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- Okubo Michihito
- Sano Kohsei General Hospital
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- Kobayashi Naoyuki
- Nierenklinik
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- Nakamura Makoto
- Sano Kohsei General Hospital
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- Naito Mareo
- Sano Kohsei General Hospital
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Abnormal lipid metabolism associated with various renal diseases has been known for a long time. Hypercholesterolemia is one of the characteristic features of nephotic syndrome, and hypertriglyceridemia is often observed in chronic renal failure (CRF). The role of lipid abnormalities in the pathogenesis of renal diseases has been variously discussed. However, direct evidence only recently became possible when more sophisticated analyses of renal histopathology as well as an application of molecular biology were introduced in the field of clinical nephrology. The recent identification of lipoprotein nephropathy (LPG), reported most often by Japanese authors since 1989, is particularly noteworthy. The detailed analysis of lipid profiles and renal histology has been instrumental in clarifying the relationship between lipids and the kidney not only in LPG but also in other disease entities such as familial-type dyslipidemias, CRF, focal glomerulosclerosis, and diabetic nephropathy. Dyslipidemias common to these diseases, together with the presence of hypertension, cause systemic atherosclerotic lesions (including lesions in the kidney) and terminal renal failure.
収録刊行物
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- Journal of Rural Medicine
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Journal of Rural Medicine 1 (2), 2_13-2_21, 2006
一般社団法人 日本農村医学会
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詳細情報 詳細情報について
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- CRID
- 1390282680231826432
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- NII論文ID
- 10018764257
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- NII書誌ID
- AA12086348
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- ISSN
- 18804888
- 1880487X
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可