Adjuvant Therapy for Breast Cancer in Kyushu
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- Wakamatsu Shinichi
- Fukuoka University Hospital
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- Mitsuyama Shoshu
- Kitakyushu Municipal Medical Center
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- Nanba Kiyoshi
- Breastpia Namba Hospital
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- Nishimura Kiyoshi
- Kumamoto City Hospital
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- Sagara Yoshiatsu
- Sagara Hospital
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- Tanaka Maki
- Social Insurance Kurume Daiichi Hospital
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- Tamaki Nobumitsu
- Naha-Nishi Clinic
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- Koga Toshihiro
- Kurume University Hospital
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- Tamura Kazuo
- Fukuoka University Hospital
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Abstract
Background: There is lack of information on the present status of adjuvant therapy for breast cancer in Kyushu. Therefore, the Kyushu Breast Cancer Study Group (KBC-SG) started registering newly diagnosed breast cancer patients who were to receive adjuvant therapy.<BR>Methods: During a period from 2001 to 2003, institutions participating in KBC-SG registered new patients who underwent curative surgical treatment for breast cancer to the registration office. One year later, the office sent them inquiries to gather any missing information.<BR>Results: A total of 2284 patients were registered from 49 institutions. The mean age was 55, ranging from 30 to 93 years, and 46% had stage I disease. Estrogen and/or progesterone receptor was positive in 71% by immunoperoxidase staining, and HER2 was expressed in 297 (33%) of 906 patients. Twenty percent of the patients underwent adjuvant radiation therapy with or without antineoplastic agents. Overall, 98% received hormonal and/or cytotoxic agents. Anthracycline-containing regimens were given to 628 of 1285 (49%) patients with chemotherapy, while 360 (28%) received oral 5-fluorouracil derivatives with or without oral cyclophosphamide.<BR>Conclusions: Anthracycline combination chemotherapy was commonly used as adjuvant therapy, but there were over a quarter of patients only given oral 5-FU derivatives, which might not be recommended by worldwide consensus. Adjuvant radiation therapy was also given to only 20% of the patients in Kyushu, which might be fewer than the report by the Japanese Breast Cancer Society. Based on these data, the KBC-SG will continue cooperative studies to improve the quality of adjuvant treatment for early breast cancer.
Journal
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- Breast Cancer
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Breast Cancer 13 (3), 308-312, 2006
The Japanese Breast Cancer Society
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Details 詳細情報について
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- CRID
- 1390282679457588992
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- NII Article ID
- 130004467455
- 10018769350
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- NII Book ID
- AA1103354X
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- ISSN
- 18804233
- 13406868
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed