A Case of Inflammatory Breast Cancer Containing the Component of Invasive Micropapillary Carcinoma

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  • MAEDA Hiroyuki
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • HONDA Kei
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • MURAKAMI Makoto
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • HIRONO Yasuo
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • GOI Takanori
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • ISHIDA Makoto
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • IIDA Atsushi
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • KATAYAMA Kanji
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • YAMAGUCHI Akio
    First Department of Surgery , Faculty of Medicine , University of Fukui
  • IMAMURA Yoshiaki
    Division of Surgical Pathology , University of Fukui Hospital

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  • Invasive micropapillary carcinomaの成分を認めた炎症性乳癌の1例

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Abstract

症例は47歳, 女性, 閉経前。右腋窩腫瘤と右乳房腫脹を主訴に, 2002年に当科を紹介受診した。右乳房全体の発赤, 硬結と両側腋窩リンパ節腫脹あり, 針生検にて硬癌と診断され, T4d, N2, M1 (LYM), 病期IVと診断した。3回の動注化学療法後, 右胸筋温存乳房切除術と左腋窩リンパ節生検を施行した。切除標本では, 右乳腺の約50%は硬癌で, 残り約50%の乳腺と両側腋窩リンパ節にinvasive micropapillary carcinoma (以下IMPCと記す) を認めた。治療開始後11カ月で, 左乳房左腋窩リンパ節転移, 胸椎転移を認め, 左胸筋温存乳房切除術と放射線治療を施行した。左乳腺, 左腋窩および左胸骨傍リンパ節に, IMPCの組織像を認めた。治療開始後1年8カ月で肝転移が出現し, 治療開始後3年1カ月で癌性髄膜炎を併発し, 永眠された。IMPCの成分を認めた稀な炎症性乳癌の1例を報告した。

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