A CASE OF ULCERATIVE COLITIS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA

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  • MIYAMOTO Masashi
    Division of Gastroenterologic and General Surgery, Asahikawa Medical College
  • KONO Toru
    Division of Gastroenterologic and General Surgery, Asahikawa Medical College
  • ONUMA Sunao
    Division of Gastroenterologic and General Surgery, Asahikawa Medical College
  • EBISAWA Yoshiaki
    Division of Gastroenterologic and General Surgery, Asahikawa Medical College
  • MAMIYA Noriaki
    Division of Gastroenterologic and General Surgery, Asahikawa Medical College
  • KASAI Shinichi
    Division of Gastroenterologic and General Surgery, Asahikawa Medical College

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Other Title
  • 特発性血小板減少性紫斑病を伴った潰瘍性大腸炎の１例

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Abstract

The patient was a 46-year-old man, who had been given medicines for ulcerative colitis (UC) since 1987 and then had been in a remission state without medication since 1998. In December 2001, he was admitted to the hospital because of recurrence of UC. His condition was improved with steroid and leucocytapheresis (LCAP). However, he developed thrombocytopenia in January 2002, and was diagnosed as having idiopathic thrombocytopenic purpura (ITP). UC and ITP were made into remission by using steroids and cyclosporin. He was admitted to the hospital again because of bloody stool in October 2002. Despite steroids and LCAP, the state of UC was resistant to medication. As for ITP, his condition was stable. Accordingly surgical treatment was applied to him in December 2002. Operative procedures included Total colectomy with ileal pouch anal anastomosis, double barreled ileostomy and splenectomy. The patient's post-operative course was uneventful. The counts of platelet have been kept within normal range.<br> It is suggested that the pathogeneses of UC and ITP are both related to the immunological process. However, the coexistence of these two diseases like in this case is rare.

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