Expression of B2-Type Cyclin-Dependent Kinase is Controlled by Protein Degradation in Arabidopsis thaliana

• Adachi, Sumiko

• Uchimiya, Hirofumi

• Umeda, Masaaki

抄録

The eukaryotic cell cycle is controlled by cyclin-dependent kinases (CDKs). Plants possess six types of CDK, among which the B-type CDK ( CDKB ) is expressed specifically from the late S- to the M-phase. We demonstrate that the expression of Arabidopsis CDKB2 is under the control of the protein degradation machinery. β-Glucuronidase fused to a putative PEST motif of CDKB2 was unstable in tobacco Bright Yellow-2 cells and Arabidopsis plants, and its degradation was arrested by the proteasome inhibitor MG132. We propose that the abundance of CDKB2 protein is regulated not only at the transcriptional level, but also through proteasome-mediated protein degradation.

This is a pre-copyedited, author-produced version of an article accepted for publication in Plant and Cell Physiology following peer review. The version of record [Plant and Cell Physiology, 47(12):1683-1686] is available online at: http://dx.doi.org/10.1093/pcp/pcl034.

収録刊行物

• Plant and Cell Physiology

  Plant and Cell Physiology 47 (12), 1683-1686, 2006-12-01

  Oxford University Press

キーワード

• PEST motif

詳細情報

• CRID: 1050014359399442816
• NII論文ID: 10018809633
• NII書誌ID: AA0077511X
• ISSN: 00320781
• HANDLE: 10061/12583
• NDL書誌ID: 8584458
• Web Site: https://naist.repo.nii.ac.jp/records/9194
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8584458
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • NDL
  • CiNii Articles