Prediction of Arterial Blood Gas Values from Venous Blood Gas Values in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

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著者

    • AK AHMET
    • Department of Emergency Medicine, Faculty of Medicine, Selcuk University
    • OGUN CEMILE OZTIN
    • Department of Anesthesiology and Intensive Care, Faculty of Medicine, Selcuk University
    • BAYIR AYSEGUL
    • Department of Emergency Medicine, Faculty of Medicine, Selcuk University
    • KAYIS SEYIT ALI
    • Department of Animal Science, Biometry Genetics Unit, Faculty of Agriculture, Selcuk University
    • KOYLU RAMAZAN
    • Department of Emergency Medicine, Faculty of Medicine, Selcuk University

抄録

Arterial blood gas (ABG) analysis has an important role in the clinical assessment of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, arterial puncture or insertion of an arterial catheter has many drawbacks. The aim of this study was to evaluate whether venous blood gas (VBG) values of pH, partial pressure of carbon dioxide (PCO<sub>2</sub>) and oxygen (PO<sub>2</sub>), bicarbonate (HCO<sub>3</sub>), and oxygen saturation (SO<sub>2</sub>) can reliably predict ABG levels in patients with AECOPD. One hundred and thirty-two patients with a prior diagnosis of COPD presenting with acute exacerbation according to AECOPD criteria were included in this prospective study. AECOPD is defined as a recent increase in cough, wheezing, the volume and purulence of sputum or shortness of breath necessitating a change in regular medication, including corticosteroids or antibiotics. ABG samples were taken immediately after venous sampling, and both were analyzed. Linear regression analysis was performed and equations were established for the estimation of arterial values. The Pearson correlation coefficients for pH, PCO<sub>2</sub>, HCO<sub>3</sub>, PO<sub>2</sub>, and SO<sub>2</sub> were 0.934, 0.908, 0.927, 0.252, and 0.296, respectively. There was a significant correlation between ABG and VBG values of pH, PCO<sub>2</sub>, and HCO<sub>3</sub> (<i>p</i> < 0.001). Linear regression equations for the estimation of pH, PCO<sub>2</sub>, and HCO<sub>3</sub> were as follows: arterial pH = 1.004 × venous pH; arterial PCO<sub>2</sub> = 0.873 × venous PCO<sub>2</sub>; and arterial HCO<sub>3</sub> = 0.951 × venous HCO<sub>3</sub>. VBG analysis can reliably predict the ABG values of pH, PCO<sub>2</sub> and HCO<sub>3</sub> in patients with AECOPD.

収録刊行物

  • THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE  

    THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 210(4), 285-290, 2006-12-01 

    Tohoku University Medical Press

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各種コード

  • NII論文ID(NAID)
    10018809763
  • NII書誌ID(NCID)
    AA00863920
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    00408727
  • データ提供元
    CJP書誌  J-STAGE 
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