Radiofrequency Ablation Therapy in Patients with Breast Cancers Two Centimeters or Less in Size

  • Oura Shoji
    Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
  • Tamaki Takeshi
    Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
  • Hirai Issei
    Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
  • Yoshimasu Tatsuya
    Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
  • Nakamura Rie
    Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
  • Okamura Yoshitaka
    Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University

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抄録

Background: Non-surgical ablation is an attractive approach as a local control method for breast cancer. The purpose of this study was to investigate the complications and efficacy of radiofrequency ablation (RFA) therapy for breast cancer.<BR>Methods: A total of 52 patients with breast cancer were enrolled. The mean tumor size was 1.3 cm (range, 0.5-2.0 cm). Under general anesthesia, RFA was done with a Cool-tip RF system after sentinel node biopsy. All patients received one session of RFA, for a maximum time of 30 minutes for the first 29 patients and 15 minutes for the following 23 patients when so-called 'break', i.e. stopping the delivery of radiofrequency, did not occur. Postoperative cytological evaluation was done 3-4 weeks after operation. Adjuvant therapy consisted of chemo- and/or endocrine-therapy and radiotherapy (50Gy).<BR>Results: The mean time of RFA was 12 minutes (5-25 minutes). One patient (2%) was troubled with a skin burn just above the ablated field. No patient had viable cancer cells on post-operative cytological evaluation. No recurrence developed 15 months on the average after RFA (6-30 months). Cosmesis after RFA was excellent in 43 patients (83%), good in 6 (12%), and fair in 3 (6%).<BR>Conclusion: RFA can be safely used for breast cancer and provides good local control and excellent cosmesis to patients with small breast cancers.

収録刊行物

  • Breast Cancer

    Breast Cancer 14 (1), 48-54, 2007

    日本乳癌学会

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