Radiofrequency Ablation Therapy in Patients with Breast Cancers Two Centimeters or Less in Size
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- Oura Shoji
- Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
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- Tamaki Takeshi
- Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
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- Hirai Issei
- Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
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- Yoshimasu Tatsuya
- Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
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- Nakamura Rie
- Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
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- Okamura Yoshitaka
- Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University
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Abstract
Background: Non-surgical ablation is an attractive approach as a local control method for breast cancer. The purpose of this study was to investigate the complications and efficacy of radiofrequency ablation (RFA) therapy for breast cancer.<BR>Methods: A total of 52 patients with breast cancer were enrolled. The mean tumor size was 1.3 cm (range, 0.5-2.0 cm). Under general anesthesia, RFA was done with a Cool-tip RF system after sentinel node biopsy. All patients received one session of RFA, for a maximum time of 30 minutes for the first 29 patients and 15 minutes for the following 23 patients when so-called 'break', i.e. stopping the delivery of radiofrequency, did not occur. Postoperative cytological evaluation was done 3-4 weeks after operation. Adjuvant therapy consisted of chemo- and/or endocrine-therapy and radiotherapy (50Gy).<BR>Results: The mean time of RFA was 12 minutes (5-25 minutes). One patient (2%) was troubled with a skin burn just above the ablated field. No patient had viable cancer cells on post-operative cytological evaluation. No recurrence developed 15 months on the average after RFA (6-30 months). Cosmesis after RFA was excellent in 43 patients (83%), good in 6 (12%), and fair in 3 (6%).<BR>Conclusion: RFA can be safely used for breast cancer and provides good local control and excellent cosmesis to patients with small breast cancers.
Journal
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- Breast Cancer
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Breast Cancer 14 (1), 48-54, 2007
The Japanese Breast Cancer Society
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Details
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- CRID
- 1390001204480534784
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- NII Article ID
- 10018815302
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- NII Book ID
- AA1103354X
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- COI
- 1:STN:280:DC%2BD2s%2FksFGisw%3D%3D
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- ISSN
- 18804233
- 13406868
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed