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- Kinoshita Satoki
- Department of Surgery, Jikei University Kashiwa Hospital
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- Yoshimoto Kazuhisa
- Department of Surgery, Jikei University Kashiwa Hospital
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- Kyoda Shigeya
- Department of Surgery, Jikei University Kashiwa Hospital
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- Hirano Akio
- Department of Surgery, Jikei University Kashiwa Hospital
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- Shioya Hisashi
- Department of Surgery, Jikei University Kashiwa Hospital
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- Kobayashi Susumu
- Department of Surgery, Jikei University Kashiwa Hospital
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- Ishiji Takaoki
- Department of Dermatology, Jikei University Kashiwa Hospital
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- Komine Kazumasa
- Department of Pathology, Jikei University Kashiwa Hospital
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- Takeyama Hiroshi
- Department of Breast & Endocrine Surgery, Jikei University School of Medicine
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- Uchida Ken
- Department of Breast & Endocrine Surgery, Jikei University School of Medicine
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- Morikawa Toshiaki
- Department of Breast & Endocrine Surgery, Jikei University School of Medicine
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- Sakamoto Goi
- Department of Breast Pathology, the Cancer Institute
この論文をさがす
抄録
We report a very rare case of malignant melanoma arising on a female nipple. A 42-year-old housewife had suffered from a small dark brown nevus on her left nipple for about thirty years without any changes. Six months before her initial visit it had begun to enlarge and rapidly changed from dark brown to black. A small bleeding ulcer was also present in the center of the lesion. Malignant melanoma rather than mammary Paget's disease was suggested based on its clinical course. Excisional biopsy was performed to differentiate between mammary Paget's disease and malignant melanoma. The histopathological examination revealed malignant melanoma, about 4 mm in thickness. She then underwent wide excision with axillary lymph node dissection. The surgical margin was made in a 3 cm radius around the biopsy site. The excision included nipple, areola, and part of the underlying breast parenchyma, adipose tissue and corresponding superficial layer of fascia. Microscopy showed metastasis in one of 13 axillary lymph nodes. After the operation, the patient received adjuvant DAV-Ferron therapy. In such a case, conserving surgery based on correct diagnosis can achieve a good cosmetic result and optimal tumor control.
収録刊行物
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- Breast Cancer
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Breast Cancer 14 (1), 105-108, 2007
日本乳癌学会
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詳細情報 詳細情報について
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- CRID
- 1390001204480542848
-
- NII論文ID
- 10018815451
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- NII書誌ID
- AA1103354X
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- COI
- 1:STN:280:DC%2BD2s%2FksFGhsw%3D%3D
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- ISSN
- 18804233
- 13406868
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可