A CASE OF GASTROINTESTINAL STROMAL TUMOR (GIST) OF THE SMALL INTESTINE PRESENTED WITH PERFORATIVE PERITONITIS

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  • 穿孔性腹膜炎にて発症した小腸GISTの1例

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Abstract

A 59-year-old man was admitted to our hospital with severe lower abdominal pain. Under the diagnosis of perforative peritonitis, emergency laparotomy was performed. There was a tumor (10cm in diameter) of the ileum and invasion of the sigmoid colon, which already was perforated. We performed a partial resection of the ileum, sigmoidectomy and colostomy. Histopathological findings showed that the tumor was composed of spindle cell proliferation. Because tumor cells were positive for c-kit and CD34, and negative for α-smooth muscle actin and S-100 protein immunohistochemically, we diagnosed the tumor as GIST of the small intestine, uncommitted type. The patient was treated with imatinib mesylate as an outpatient.

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