Relationship between Sleep-Disordered Breathing and Lifestyle-related Illnesses in Subjects Who Have Undergone Health-screening

• Okada Mitsuyo

  First Department of Internal Medicine, Shinshu University

• Takamizawa Akemi

  Respiratory Division, JA Nagano Koseiren Shinonoi General Hospital

• Tsushima Kenji

  First Department of Internal Medicine, Shinshu University

• Urushihata Kazuhisa

  First Department of Internal Medicine, Shinshu University

• Fujimoto Keisaku

  First Department of Internal Medicine, Shinshu University

• Kubo Keishi

  First Department of Internal Medicine, Shinshu University

Abstract

Objective: Simplified sleep polysomnography was performed in 207 adult men to examine the relationship between the frequency of sleep-disordered breathing (SDB) and lifestyle-related illness.<br> Methods: Each subject was checked for SDB using a simplified sleep polysomnograph (Auto-Set Portable; Teijin Limited, Tokyo, Japan). Apnea and hypopnea were detected with a nasal cannula type airflow sensor. Hypoxemia was checked with a percutaneous oxygen saturation (SpO₂) monitor. We analyzed the relationships between SDB and body mass index (BMI) and hypertension, hyperlipidemia, liver dysfunction, fatty liver, and abnormal glucose metabolism.<br> Results: Fifty-nine subjects (29%) showed SDB with apnea hypopnea index (AHI) over 15 times/h. The frequency of obesity (BMI≥25), hypertension, hypercholesterolemia, fasting blood glucose level, and HbA1c were significantly higher in patients with SDB than in normal individuals (AHI<5 times/h). The frequencies of hypertension, hyperlipidemia, and abnormal glucose metabolism were compared between the obesity-free normal AHI group and the SDB group, and only that of hypertension was significantly different between the two groups.<br> Conclusions: The present study revealed a high frequency of SDB among Japanese individuals. The results also suggest that as SDB becomes severe, it becomes more closely linked to the onset of lifestyle-related illnesses, such as hypertension, hypercholesterolemia and abnormal glucose metabolism.<br>

Journal

• Internal Medicine

  Internal Medicine 45 (15), 891-896, 2006

  The Japanese Society of Internal Medicine

Keywords

• sleep disordered breathing (SDB)
• lifestyle-related illness

Details

• CRID: 1390282679847535104
• NII Article ID: 10018831868
• NII Book ID: AA10847079
• DOI: 10.2169/internalmedicine.45.1592
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/45/15/45_15_891/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007232599
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed