Classification of early arthritis patients and how to determine disease severity

• KAWAKAMI Atsushi

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

• TAMAI Mami

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

• EGUCHI Katsumi

  First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University

Bibliographic Information

Other Title

• 早期関節炎の捉え方と病態解析の方向性

Abstract

  Recent clinical studies of rheumatoid arthritis reveal that therapeutic intervention early in rheumatoid arthritis leads to less joint damage, indicating the importance of early diagnosis of RA for improvement of prognosis. According to the data of our “Early Arthritis Prospective Cohort”, we have found that early arthritis patients, described as undifferentiated arthritis, progress to rheumatoid arthritis at high frequency if the patients positive with anti-cyclic citrullinated peptide antibody (anti-CCP antibody) and bone marrow edema at the entry. In addition, we are going to classify the pathologic status (disease severity) of early arthritis patients by serologic variables, radiographic findings and genetic analysis.<br>

Journal

• Japanese Journal of Clinical Immunology

  Japanese Journal of Clinical Immunology 30 (1), 37-40, 2007

  The Japan Society for Clinical Immunology

Keywords

• rheumatoid arthritis
• anti-CCP antibody
• MRI
• bone marrow edema
• genetic analysis

Details

• CRID: 1390282679626526208
• NII Article ID: 10018858068
• NII Book ID: AN00357971
• DOI: 10.2177/jsci.30.37
• ISSN: 13497413
• ISSN: 09114300
• HANDLE: 10069/24072
• Web Site: https://nagasaki-u.repo.nii.ac.jp/records/14097
• Web Site: http://www.jstage.jst.go.jp/article/jsci/30/1/30_1_37/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007179173
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed