頬部に生じた孤立性神経線維腫の1例 A case of solitary neurofibroma in the cheek
Neurofibroma is a benign tumor originating from Schwann cells, perineural fibroblasts, or both. It is commonly associated with neurofibromatosis (von Recklinghausen's disease), while solitary neurofibroma rarely occurs in the oral region. We report a rare case of solitary neurofibroma arising in the cheek. The patient was a 47-year-old woman who had no symptoms, except for a painless swelling in the right side of the cheek. We found neither cafe-au-lait spots nor tumors on the skin of her body. Intraoral examination revealed a solitary, mobile, welldelimited, elastic soft mass 25 mm in diameter in the cheek. CT scan revealed an enhanced tumor mass in the cheek. The tumor was surgically removed. Histopathologically, it was composed of proliferating spindle cells and collagen-like fibers. Immunohistochemical studies showed positive staining of tumor cells with S-100 protein. The histopathological diagnosis was neurofibroma. About 12 months after the operation, there is no evidence of recurrence.
日本口腔外科学会雑誌 52(11), 592-595, 2006-11-20
Japanese Society of Oral and Maxillofacial Surgeons