下顎骨に転移した頭蓋底原発悪性顆粒細胞腫の1例 A case of malignant granular cell tumor of the mandible metastasizing from the skull base
A 57-year-old man underwent surgical excision of a skull base tumor in 1996, which was diagnosed as a granular cell tumor histopathologically. Gamma knife radiosurgery was performed for a recurrent tumor in 2000. A recurrent tumor developed from the right infratemporal fossa and underwent gamma knife radiosurgery againin 2001. He visited our department in 2002 because of swelling and pain in the left side of the mandible. Panoramic radiography revealed a radiolucency (35mm×50mm) with an ill-defined border in the body of the left side of the mandible. The histopathological diagnosis of a biopsy specimen was a malignant granular cell tumor. Radiosurgery with a Cyber knife was performed. Metastases to the liver and pancreas were detected during follow-up. Although adequate control of the metastatic site of the mandible was obtained, the patient died of arterial bleeding from necrotic tissue of the mandible and cachexia 10 months after radiosurgery with the Cyber knife.
日本口腔外科学会雑誌 52(11), 606-610, 2006-11-20
Japanese Society of Oral and Maxillofacial Surgeons