二重濾過血漿交換法が有効であった口腔粘膜尋常性天疱瘡の1例 A case of pemphigus vulgaris of the oral mucosa that responded to double-filtration plasmapheresis

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Pemphigus vulgaris (PV) is an autoimmune disease with intractable massive blisters of the skin or mucosa. Patients with oral mucosal lesions often cannot eat because of unbearable pain. Although steroids and immunosuppressants are commonly used to PV, these therapies are ineffective or cannot be continued because of side effects in some patients. We reported a case of the PV of the upper and lower gingiva in which treatment with predonisolone and cyclosporine A was ineffective, but double filtration plasmapheresis (DFPP) was effective. The patient was a 36-year-man who could not eat anything at presentation. After treatment, oral intake became possible because pain of the oral mucosa had resolved. In this patient, the anti-desmoglein 3 antibody in blood decreased with the resolution of clinical symptoms.

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  • 日本口腔外科学会雑誌  

    日本口腔外科学会雑誌 52(10), 556-559, 2006-10-20 

    Japanese Society of Oral and Maxillofacial Surgeons

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各種コード

  • NII論文ID(NAID)
    10018859240
  • NII書誌ID(NCID)
    AN00189163
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00215163
  • NDL 記事登録ID
    8551055
  • NDL 雑誌分類
    ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL 請求記号
    Z19-145
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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