慢性硬化性下顎骨骨髄炎の臨床的検討―外側皮質骨除去術および動注療法併用例について―

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  • Clinical observations of mandibular chronic osteomyelitis: combination therapy with decortication and intra-arterial infusion of antibiotics
  • ショウレイ ホウコク マンセイ コウカセイ カガクコツ コツズイエン ノ リンショウテキ ケントウ ソトガワ ヒシツコツ ジョキョジュツ オヨビ ドウ チュウ リョウホウ ヘイヨウレイ ニ ツイテ
  • combination therapy with decortication and intra-arterial infusion of antibiotics
  • 外側皮質骨除去術および動注療法併用例について

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Mandibular chronic osteomyelitis with diffuse osteosclerosis is recognized as an intractable infectious disease. We employed decortication and intra-arterial infusion of antibiotics to treat 6 cases.<BR>Decortication of the affected mandible was performed with retrograde catherization to the superficial temporal artery of the affected side with the patient under general anesthesia. Antibiotics, IPM/CS or FMOX, were given intra-arterially for 4 to 11 days. In addition, FMOX and PIPC were administered intravenously for 8 to 17 days. CT and MRI were performed postoperatively. Postoperative follow-up ranged from 1 year 6 months to 2 years 5 months.<BR>Postoperative MRI showed that bone marrow signals recovered to nearly normal in 4 cases. High-signal areas of bone marrow and osteosclerotic changes remained in 2 cases, but showed improvement.<BR>The results were satisfactory, without recurrence in any of the 6 cases.

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