上顎に発生したNK/Tリンパ腫の1例 A case of NK/T cell lymphoma in the upper jaw

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著者

    • 池田 哲也 IKEDA Tetsuya
    • 杏林大学医学部耳鼻咽喉科・顎口腔科 Department of Otorhinolaryngology, Oral Surgery, Kyorin University School of Medicine
    • 宮沢 正純 MIYAZAWA Masazumi
    • 杏林大学医学部耳鼻咽喉科・顎口腔科 Department of Otorhinolaryngology, Oral Surgery, Kyorin University School of Medicine
    • 甲能 直幸 KOHNO Naoyuki
    • 杏林大学医学部耳鼻咽喉科・顎口腔科 Department of Otorhinolaryngology, Oral Surgery, Kyorin University School of Medicine

抄録

A 62-year-old man with an NK/T lymphoma originating in the right side of the upper jaw showed destruction of the hard palate and sino-nasal cavity. Intraoral examination revealed an ulcer with necrotic mucosa covering the area from the right side of the upper gingiva to the midline of the palate. CT scanning demonstrated a lesion on the right side of the sino-nasal cavity, and other clinical findings suggested a lethal midline granuloma. A biopsy specimen was positive for CD3, CD56, and Epstein-Barr virus (EBV), but negative for CD20. On the basis of these findings, a definitive diagnosis of NK/T lymphoma was established, and a course of radiation treatment was prescribed. Thereafter, his general condition deteriorated rapidly, and the patient died approximately 4 months later. In this disease, it is very difficult to establish a correct diagnosis. In situ hybridization study for EBV can contribute to the diagnosis because it can detect very small numbers of neoplastic cells in the early stage of disease.

収録刊行物

  • 日本口腔外科学会雑誌  

    日本口腔外科学会雑誌 52(6), 346-349, 2006-06-20 

    Japanese Society of Oral and Maxillofacial Surgeons

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各種コード

  • NII論文ID(NAID)
    10018859751
  • NII書誌ID(NCID)
    AN00189163
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00215163
  • NDL 記事登録ID
    8009460
  • NDL 雑誌分類
    ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL 請求記号
    Z19-145
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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