上下顎骨に発生し感染を伴った骨 Paget 病の1例 A case of Paget's disease of bone with bacterial infection in both maxillary and mandibular bone
Paget's disease of bone is characterized by excessive bone resorption in focal areas, followed by new bone formation. The etiology of the disease is not well understood. We report a case of Paget's disease of bone with bacterial infection in both maxillary and mandibular bone. A 48-year-old woman visited our hospital because of pain in the left side of the mandible in November 1991. We removed an impacted supernumerary tooth and sequestrum from the premolar region. She returned to our hospital because of pus discharge from the inferior border of the left side of the mandible in April 2000. Orthopantomography revealed a cotton-wool appearance and sequestra in both maxillary and mandibular bone. The sequestra were surgically removed. The patient returned again because of pain and swelling of the right upper alveolar gingiva in September 2004. Orthopantomography revealed a cotton-wool appearance and sequestra in the right side of the maxilla. We removed the sequestra and performed a biopsy of the bone around the sequestra. A histological diagnosis of Paget's disease of bone was made on the basis of a mosaic pattern with osteogenic and osteoclastic reactions.
日本口腔外科学会雑誌 52(6), 350-353, 2006-06-20
Japanese Society of Oral and Maxillofacial Surgeons