顎変形症手術の術後痛と周術期のストレス関連ホルモンの動態について Postoperative pain and stress-related hormone responses to surgery in jaw deformities
In recent years, surgery for jaw deformities has become common practice in the field of oral surgery, but few reports have discussed countermeasures for postoperative pain or perioperative stress-related biological responses. Nonsteroidal anti-inflammatory drugs (NSAIDs) are usually used for postoperative analgesia, but pain relief is often insufficient. We investigated the responses of stress-related hormones and assessed pain caused by surgery in patients with jaw deformities to ascertain postoperative pathological changes, which have an important role in selecting the postoperative analgesic technique. This investigation demonstrated not only severe pain, but also increases in blood concentrations of stress-related hormones such as catecholamines, vasopressin, and cortisol immediately after surgery. Therefore, when surgically treating jaw deformities, administration of analgesics mustbe started during surgery, taking into account postoperative analgesia and carefully monitoring postoperative changes in vital signs.
日本口腔外科学会雑誌 52(3), 162-166, 2006-03-20
Japanese Society of Oral and Maxillofacial Surgeons