書誌事項
- タイトル別名
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- Development of Industrial Process for Optically Active Propanol Derivatives and Their Applications
- コウガク カッセイ プロパノール ユウドウタイ ノ コウギョウテキ セイホウ ノ カイハツ ト ソノ オウヨウ
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As optically active compounds are playing important roles in a living body as diverse components of bioactive materials, they are mainly utilized in the pharmaceutical field. Going with the stream of the huge advance in chiral technology, we have developed the industrial process to produce optically active propanols by stereoselective assimilation of racemic ones with microorganisms. In addition to that, we have industrialized the technology of hydrolytic kinetic resolution catalyzed by chiral salen complex to prepare optically active epichlorohydrin, and expanded our technical field. Furthermore, we have tried to spread our series of optically active C 3 and C 4 compounds derived from such propanol derivatives. In this paper, investigation of the industrial process for not only the optically active basic chiral propanol derivatives but also chiral building blocks and pharmaceutical intermediates will be discussed, combining our efforts to prevent racemization in the reaction and so on.
収録刊行物
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- 有機合成化学協会誌
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有機合成化学協会誌 65 (4), 308-319, 2007
公益社団法人 有機合成化学協会
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詳細情報 詳細情報について
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- CRID
- 1390001205312637824
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- NII論文ID
- 10018898591
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- NII書誌ID
- AN0024521X
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- ISSN
- 18836526
- 00379980
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- NDL書誌ID
- 8788609
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可