Portable Antigen Detector Using Blue Laser Diodes and Quantum Dots
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We developed a portable antigen detecting system based on laser illuminated fluorescence microscopy. The introduction of small and reliable semiconductor laser and charge coupled device (CCD) camera enable to make a compact antigen detecting system. The 532 nm green laser used as light sources can excite the 655 and 705 nm quantum dots attached to antibody connecting to target antigen. The light emitted by the excited quantum dots forms an image in CCD camera. The fluorescence image successfully delineates the antigen distribution in the specimen. We demonstrate the same performance using a 405 nm laser diode which can excite wider range of emission wavelength of quantum dots.
- Jpn J Appl Phys
Jpn J Appl Phys 46(4A), 1763-1767, 2007-04-15
INSTITUTE OF PURE AND APPLIED PHYSICS