Whitening Effect of Shochu Distillation Remnants: Inhibitory Effects on the Production of Melanins and Tyrosinase Activity

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  • Komizu Yuji
    Division of Applied Life Science, Graduate School of Engineering, Sojo University
  • Tomonaga Yuka
    Division of Applied Life Science, Graduate School of Engineering, Sojo University
  • Tanoue Osamu
    Division of Applied Life Science, Graduate School of Engineering, Sojo University
  • Ueoka Ryuichi
    Division of Applied Life Science, Graduate School of Engineering, Sojo University

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  • 焼酎粕有効成分の美白効果に関する基礎研究
  • ショウチュウ カス ユウコウ セイブン ノ ビハク コウカ ニ カンスル キソ ケンキュウ

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Abstract

Today's cosmetics market in Japan is seeing a strong demand for whitening agents from women wishing to remove pigmentations from facial skin. At the same time, we and other researchers are trying to produce useful materials (e.g., medicines and cosmetics) from the distillation remnants of shochu spirits, because the disposal of these remnants in the sea will be prohibited from 2007. In the present study, we carried out basic research for development of a cosmetic whitening agent from powdered barley shochu distillation remnants using B16-F0 melanoma cells at a safe low density of 10 μg/mL. The findings were as follows: (1) B16-F0 melanoma cells were visibly whitened; (2) melanin production by the cells was markedly depressed; and (3) tyrosinase activity of the cells was strongly inhibited. These findings indicate the potential applicability of powdered barley shochu distillation remnants in cosmetic whitening agents.

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