Clinical and microbiological evaluations of children with hypophosphatasia affected by periodontitis
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- Miyamoto Eriko
- Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry
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- Nakano Kazuhiko
- Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry
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- Tamura Kiyoko
- Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry
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- Nomura Ryota
- Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry
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- Sasaki Yumi
- Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry
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- Ooshima Takashi
- Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry
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Four patients with hypophosphatasia, including twin brothers and younger and older sisters, were analyzed longitudinally. Ten periodontitis-related bacterial species in dental plaque were detected using a Polymerase chain reaction (PCR) method with species-specific sets of primers. Further, clinical parameters related to periodontal conditions were recorded at each visit. One of the twins, who had experienced early exfoliation of the primary teeth, had a greater number of bacterial species than his brother, who had no alveolar bone loss. Both of the sisters experienced early exfoliation of their primary teeth, and the average numbers of tested bacterial species were higher in other subjects of the same age. Our results indicate that impaired cementum tissue caused by hypophosphatasia may produce favorable sites for colonization of periodontitis-related bacteria.
収録刊行物
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- Pediatric Dental Journal
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Pediatric Dental Journal 17 (1), 84-92, 2007
一般社団法人 日本小児歯科学会
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詳細情報
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- CRID
- 1390001204383824640
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- NII論文ID
- 130004475822
- 10018904626
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- NII書誌ID
- AA10809637
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- ISSN
- 18803997
- 09172394
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可